вторник, 14 февраля 2012 г.

Новое исследование связи гиповитаминоза D с симптомами депрессии

February 13, 2012 — A large cross-sectional study of adults suggests a link between low vitamin D levels and depressive symptoms, particularly in individuals with a history of depression.
Because the relationship between low vitamin D levels and depression was stronger in those with a prior history of depression, "it may be more of a marker for relapse than for new-onset," senior investigator E. Sherwood Brown, MD, PhD, head of the psychoneuroendocrine research program at the University of Texas Southwestern Medical Center, Dallas, toldMedscape Medical News.
More Evidence Links Low Vitamin D to Depression 

четверг, 2 февраля 2012 г.

Наркотерапия изофлюраном

Treatment-refractory depressed patients who objected to electroconvulsive therapy (ECT) were given a series of anesthesias with isoflurane (Forane®), a modern and established inhalation anesthetic. According to our hypothesis to be tested, the brief period of electrocerebral silence (ES), which can be observed shortly after the grand mal seizure in ECT, may be in itself a crucial biological determinant for the therapeutic effects of ECT. Isoflurane is the only drug known to effect an ES in the EEG in nontoxic concentrations, which does not result in adverse effects on any body organ including the brain; no seizure activity can be observed. Eleven depressed patients received a total of 36 anesthesias with isoflurane (ES narcotherapy). Rapid antidepressant effects were observed in 9 patients (p < 0.0001). Effects were reproducible and lasted up to several weeks. No adverse effects of anesthesia were noticed.
Rapid Psychotherapeutic Effects of Anesthesia with Isoflurane (ES Narcotherapy) in Treatment-Refractory Depressed Patients

Исход шизофрении и потребление сахара

The most consistent finding is that a greater consumption of refined sugar is associated with a worse outcome of schizophrenia and a greater prevalence of depression.