"This study elegantly demonstrates how memantine is able to protect neurons without causing harmful side effects," said Giles E. Hardingham, BSc, PhD, professor of molecular neurobiology, University of Edinburgh in the United Kingdom, who was not involved in the study.
"Memantine only blocks NMDA receptors when they are engaged in harmful activities away from the synapse; it does not interfere with the normal functioning of the NMDA receptor at the synapse," Dr. Hardingham explained.
Memantine's Unique Mechanism of Action Uncovered
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