The sensitivity analysis demonstrated only a small potential confounding effect on the association between asthma and suicide. But Ferri said it is possible that depression may play a mediating role in suicide—individuals who developed depression after baseline might, for instance, have been more likely to interpret respiratory symptoms as a serious medical disorder, especially when symptoms were persistent and severe. (The sensitivity analysis is posted online at AJP in Advance as a data supplement to the article.)
Asthma, Air Pollution Linked to Increased Suicide Risk
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