A total of 73 adults were enrolled in this six-week study and randomly assigned to the placebo control group or the SAM-e treatment group.
SAM-e, in combination with standard depression treatment, was more effective than antidepressant treatment alone in improving measures of depression and remission rates of patients with significant clinical depression. SAM-e-treated subjects had a greater response and remission rate to treatment than the placebo-treated group. SAM-e was well-tolerated with no reported adverse reactions.
Dietary Supplement SAM-e Aids Treatment of Depression
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