четверг, 15 марта 2012 г.

Литий и циркадные ритмы

According to Dr. Qing-Jun Meng in the university’s Faculty of Life Sciences, the extreme mood swings in bipolar disorder are associated with disruptions in circadian rhythms — the 24-hour rhythms controlled by our body clocks that govern our day and night activity.
“By tracking the dynamics of a key clock protein, we discovered that lithium increased the strength of the clockwork in cells up to threefold by blocking the actions of an enzyme called glycogen synthase kinase or GSK3,” he said.
Lithium Impacts Bipolar Disorder by Strengthening Body Clock 

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