Эффективность битопертина не подтвердилась

FlashLyte and DayLyte, the first 2 studies discontinued in January 2014, were evaluating bitopertin for negative symptoms, including lack of motivation and social withdrawal. Suboptimally controlled symptoms include hallucinations and delusions.

The primary endpoints were negative symptom factors scores on the Positive and Negative Symptom Scale (PANSS) after 24 weeks of adjunctive treatment with bitopertin vs placebo. Although the active treatment was found to be well tolerated, the PANSS score changes from baseline were not found to be statistically significant.

Bitopertin Disappoints as Schizophrenia Treatment