Symptoms and Signs Suggestive of Testosterone Deficiency in Men
More Specific Signs and Symptoms
– Reduced libido – Erectile dysfunction (ED) – Reduced intensity of orgasm and genital sensation – Osteoporosis or low bone mineral density – Decreased spontaneous erection – Oligospermia or azoospermia – Very small or shrinking testes – Hot flushes, sweats – Breast discomfort, gynecomastia – Loss of pubic and axillary hair, reduced shaving Less Specific Signs and Symptoms – Decreased energy or vitality, increased fatigue – Depressed mood – Reduced muscle mass and strength – Poor concentration and memory – Sleep disturbance; increased sleepiness – Mild anemia – Increased body fat, body mass index – Diminished physical or work performance |
Risks and Comorbid Illnesses Associated With Testosterone Deficiency
– Metabolic syndrome
– Obesity – Hyperlipidemia – Hypertension – Elevated fasting plasma glucose and serum insulin – Elevated C-reactive protein – Diabetes mellitus (type 1 or 2) – Cardiovascular disease (including aortic atherosclerosis) – Chronic obstructive lung disease – Inflammatory arthritis – Low trauma fracture – End-stage renal disease – HIV-related weight loss – Hemochromatosis – Sellar mass, radiation to the sellar region, or other diseases of the sellar region – Chronic pain syndrome and treatment with opioids – Treatment with glucocorticoids – Radical prostatectomy |
Low Testosterone Medscape CME Expert Column Series. Issue 1: Testosterone Deficiency in Men: Common and Under-recognized
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