They then confirmed these effects in a human population. Depressed individuals who reported anti-inflammatory drug use were much less likely to have their symptoms relieved by an antidepressant than depressed patients who reported no anti-inflammatory drug use.
The effect was rather dramatic since, in the absence of any anti-inflammatory or analgesic use, 54 percent of patients responded to the antidepressant, wheh success rates dropped to approximately 40 percent for those who reported using anti-inflammatory agents.
Anti-Inflammatory Meds Can Reduce Antidepressant Effectiveness
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